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Blood sampling to assess production of antigen-specific antibodies after immunization is commonly performed, but it presents logistical difficulties for trials carried out during an infectious disease outbreak. In this study, we show that antibodies may be reliably detected in oral fluid collected in a minimally invasive manner without use of sharps. Clinical Trials Registration. NCT02240875.

Original publication

DOI

10.1093/ofid/ofw031

Type

Journal article

Journal

Open Forum Infect Dis

Publication Date

01/2016

Volume

3

Keywords

Ebola vaccine, antibodies, oral fluid, serology