We present the case of a 3-year-old boy who was diagnosed with cerebral abscesses due to Aspergillus nidulans infection on day 28 of induction chemotherapy for acute lymphoblastic leukemia. He responded well to treatment with voriconazole and caspofungin, making a full recovery. There are very few cases of invasive aspergillosis reported in children during induction chemotherapy for acute leukemia and A. nidulans is rare in the absence of chronic granulomatous disease.

Original publication

DOI

10.1097/MPH.0000000000000351

Type

Journal article

Journal

J Pediatr Hematol Oncol

Publication Date

08/2015

Volume

37

Pages

e384 - e386

Keywords

Antifungal Agents, Aspergillosis, Aspergillus nidulans, Brain Abscess, Child, Preschool, Echinocandins, Humans, Induction Chemotherapy, Lipopeptides, Lung Diseases, Fungal, Male, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Prognosis, Voriconazole