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Immunocompromised children have a higher risk of developing infections and associated higher rates of mortality and morbidity. Although this group could benefit the most from vaccine administration, specific considerations regarding immunisations are required. This review is a summary of the vaccines that are relevant to the immunocompromised host, covering both live and non-live vaccines. The burden of disease, safety, immunogenicity/effectiveness and specific recommendations for each vaccine are described as well as specific guidelines from different organisations.

Original publication




Journal article


The Journal of infection

Publication Date



72 Suppl


S13 - S22


Oxford Vaccine Group, Department of Paediatrics, University of Oxford, OX3 7LE, United Kingdom. Electronic address:


Humans, Vaccines, Vaccines, Inactivated, Immunization, Immunocompromised Host, Child, Infant, Practice Guidelines as Topic, Vaccines, Live, Unattenuated, Immunogenicity, Vaccine