Rhinoviruses (RV) are ubiquitous respiratory tract pathogens. They affect both the upper and lower respiratory tract and cause colds but have also been associated with wheezing, asthma exacerbations and pneumonia. New blood transcription profiling techniques of the host immune response are becoming available to characterise the pathogenesis of RV in humans. This review will outline the clinical impact of RVs in children.
Journal article
The Journal of infection
06/2017
74 Suppl 1
S41 - S46
Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the NIHR Oxford Biomedical Research Centre, Level 2, Children's Hospital, Oxford OX3 9DU, UK. Electronic address: simon.drysdale@paediatrics.ox.ac.uk.
Humans, Rhinovirus, Pneumonia, Viral, Common Cold, Asthma, Respiratory Sounds