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Search results (27)

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Rapid clonal selection within early hematopoietic cell compartments presages the outcome of ivosidenib combination therapy.

Turkalj S. et al, (2026), Blood, 147, 613 - 632

Rapid clonal selection within early hematopoietic cell compartments presages outcome to ivosidenib combination therapy

Turkalj S. et al, (2024)

Hematopoietic stem cell heterogeneity and age-associated platelet bias are evolutionarily conserved.

Aksöz M. et al, (2024), Sci Immunol, 9

Selective advantage of mutant stem cells in human clonal hematopoiesis is associated with attenuated response to inflammation and aging.

Jakobsen NA. et al, (2024), Cell Stem Cell, 31, 1127 - 1144.e17

Selective advantage of mutant stem cells in clonal hematopoiesis occurs by attenuating the deleterious effects of inflammation and aging

Jakobsen NA. et al, (2023)

Identification and Age-dependent Increase of Platelet Biased Human Hematopoietic Stem Cells

Aksöz M. et al, (2022)

Single-Cell Analysis of Human Clonal Hematopoiesis Identifies Distinct Impact of DNMT3A and TET2 mutations on Hematopoietic Differentiation

Jakobsen NA. et al, (2022), BLOOD, 140, 2227 - 2228

Oncogenic Gata1 causes stage-specific megakaryocyte differentiation delay.

Juban G. et al, (2021), Haematologica, 106, 1106 - 1119

phase Ib/II study of ivosidenib with venetoclax plus /- azacitidine in IDH1-mutated myeloid malignancies.

Lachowiez CA. et al, (2021), JOURNAL OF CLINICAL ONCOLOGY, 39

Mechanisms of response and resistance to AML therapies

Stoilova B. et al, (2020), Clinical Lymphoma, Myeloma & Leukemia, 20, S7 - S7

C/EBPalpha and GATA-2 mutations induce bi-lineage acute erythroid leukemia through transformation of a neomorphic neutrophil-erythroid progenitor

NERLOV C. et al, (2020), Cancer Cell

Phase Ib/II study of the IDH1-mutant inhibitor ivosidenib with the BCL2 inhibitor venetoclax plus /- azacitidine in IDH1-mutated hematologic malignancies.

Lachowiez CA. et al, (2020), JOURNAL OF CLINICAL ONCOLOGY, 38

OncogenicGata1causes stage-specific megakaryocyte differentiation delay

Juban G. et al, (2019), Haematologica: the hematology journal

Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome.

Labuhn M. et al, (2019), Cancer cell, 36, 340 - 340

The Inflammasome: More Than a Protective Innate Immune Mechanism

(2019), Immunity

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