Senior Research Associate
Christoph Blohmke obtained his PhD in Experimental Medicine from the University of British Columbia, Canada. In his PhD he studied the host-pathogen interaction in Cystic Fibrosis lung disease to understand the pulmonary innate immune system in order to identify novel targets for anti-inflammatory therapy. Prior to moving to Canada, he graduated from the University of Lubeck with a BSc in Molecular Biotechnology before completing an MSc program in Medical Biochemistry at the University of Amsterdam. He joined the Oxford Vaccine Group in October 2011 to study the human immune response to S. Typhi.
Interferon-driven alterations of the host’s amino acid metabolism in the pathogenesis of typhoid fever
Blohmke CJ. et al, Journal of Experimental Medicine
Design, recruitment, and microbiological considerations in human challenge studies.
Darton TC. et al, (2015), Lancet Infect Dis, 15, 840 - 851
The use of systems biology and immunological big data to guide vaccine development.
Blohmke CJ. et al, (2015), Genome Med, 7
Gene expression profiles are different in venous and capillary blood: Implications for vaccine studies.
Stein DF. et al, (2016), Vaccine
Using a Human Challenge Model of Infection to Measure Vaccine Efficacy: A Randomised, Controlled Trial Comparing the Typhoid Vaccines M01ZH09 with Placebo and Ty21a.
Darton TC. et al, (2016), PLoS neglected tropical diseases, 10, e0004926 - e0004926
Oral Challenge with Wild-Type Salmonella Typhi Induces Distinct Changes in B Cell Subsets in Individuals Who Develop Typhoid Disease.
Toapanta FR. et al, (2016), PLoS neglected tropical diseases, 10, e0004766 - e0004766
Salmonella Typhi-specific multifunctional CD8+ T cells play a dominant role in protection from typhoid fever in humans.
Fresnay S. et al, (2016), J Transl Med, 14
Development and Evaluation of a Blood Culture PCR Assay for Rapid Detection of Salmonella Paratyphi A in Clinical Samples.
Zhou L. et al, (2016), PLoS One, 11