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University of Oxford researchers working in an unprecedented vaccine development effort to prevent COVID-19 have started screening healthy volunteers (aged 18-55) today for their upcoming ChAdOx1 nCoV-19 vaccine trial in the Thames Valley Region. The vaccine based on an adenovirus vaccine vector and the SARS-CoV-2 spike protein is already in production but won’t be ready for some weeks still.
Disease-Attenuated Pneumococcal Biosynthesis Gene Mutants Invade the Mucosal Epithelium and Induce Innate Immunity.
Journal article
Weight CM. et al, (2026), J Infect Dis
Recent Advances, Bottlenecks, and Future Directions in Plasmodium falciparum Vaccine Development.
Journal article
Turan G. et al, (2026), Vaccines (Basel), 14
Optimising DTwP-containing vaccine infant immunisation schedules in Uganda and Nepal (OptImms): two open-label, non-inferiority, randomised controlled trials.
Journal article
Bijukchhe SM. et al, (2026), Lancet Infect Dis
Report of a one-day convening on regulatory science, practices, and innovative approaches to facilitate approval of novel combination vaccines.
Journal article
Hausdorff WP. et al, (2026), Vaccine, 75
The Epidemiology and Clinical Burden of Human Adenovirus Respiratory Infections Among Hospitalized Children Under 5 Years in Jordan.
Journal article
Abu-Helalah M. et al, (2026), Pediatr Infect Dis J, 45, 229 - 235
Severe necrotizing soft tissue infections (SENSEI) study: Protocol for a multi-centered audit.
Journal article
Yoshimura R. et al, (2026), JPRAS Open, 48, 331 - 336
Securing the future of immunisation: ESCMID’s vision
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Ramasamy MN. et al, (2026), CMI Communications, 3, 105167 - 105167
Pneumococcal colonisation and mucosal immunity in adults with asthma following experimental human challenge
Journal article
Reiné J. et al, (2026), BMJ Immunology, 1, e000012 - e000012
Maternal perspectives on the RSV vaccine (Abrysvo): a thematic analysis of survey findings from the first season of implementation in England and Scotland.
Journal article
O'Hagan S. et al, (2026), Arch Dis Child
Pooled analysis of PCV13 efficacy from controlled human infection trials in Malawi and the UK.
Journal article
Kudowa E. et al, (2026), NPJ Vaccines
An Adenoviral Vectored Vaccine Protects Mice Against Aerosol Challenge with Yersinia pestis.
Journal article
Dold C. et al, (2026), Mol Ther
Predicting Salmonella Typhi incidence using prevalence metrics from sentinel studies of community-onset bloodstream infections
Preprint
Hagedoorn N. et al, (2026)
Controlled human pneumococcal infection in the Netherlands: Colonisation, antibody responses and the impact of viral co-infection.
Journal article
van Beek LF. et al, (2026), J Infect, 92
Maternal iron status and total immunoglobulin-G influence transplacental antibody transfer across eight diverse geographical settings.
Journal article
Tiley KS. et al, (2026), Vaccine, 73
Biobanking knowledge and donation willingness among musculoskeletal patients in England: a multisite cross-sectional study.
Journal article
Boakye Serebour T. et al, (2026), BMJ Open, 16
Enablers and barriers to participation in vaccine trials: a narrative synthesis.
Journal article
Daniel N. et al, (2026), Vaccine, 73
The effect of pneumococcal conjugate vaccine and pneumococcal polysaccharide vaccine on nasopharyngeal colonisation following human infection challenge with serotype 3 and serotype 6B (PREVENTING PNEUMO 2): a double-masked, randomised, controlled, phase 4 trial.
Journal article
Liatsikos K. et al, (2026), Lancet Microbe
A risk to child health: confusion and concern over changes to US vaccine policy.
Journal article
Pollard AJ. and Plotkin S., (2026), Lancet, 407, 553 - 556
Rapid clonal selection within early hematopoietic cell compartments presages the outcome of ivosidenib combination therapy.
Journal article
Turkalj S. et al, (2026), Blood, 147, 613 - 632