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Solving the riddle of the typhoid toxin

Solving the riddle of the typhoid toxin

Research

Salmonella Typhi bacteria can invade the intestines and blood and lead to a disease called typhoid fever – a disease that affects around 11 million people each year globally.

The global value of vaccination

The global value of vaccination

General

We recently worked with Mediaplanet on the 2019 Health Awareness: Value of Vaccines campaign. The campaign features exclusive content from key thought leaders and industry voices about the critical importance of full immunisation throughout life.

Should vaccines be made compulsory

Should vaccines be made compulsory?

Dr Samantha Vanderslott (Oxford Vaccine Group), Dr Eleanor Draeger (sexual health expert and medical writer), and Professor Beate Kampmann (London School of Hygiene and Tropical Medicine) debate compulsory vaccination. Presented by Philippa Thomas on BBC World service.

The key to better childhood vaccines might be in our dna

The key to better childhood vaccines might be in our DNA

Publication Research

PBS features Daniel O'Connor's research on how children's genetic profiles affect their immunity.

Paediatrics celebrates international clinical trials day

Paediatrics celebrates International Clinical Trials Day

Public Engagement

Sign up to take part in our clinical trials, talk to the research staff, or simply enjoy a Microbe Mugshot Match or a Game of Crohn's (Disease).

How was typhoid eliminated in the past

How was typhoid eliminated in the past?

Public Engagement Research

Drs Samantha Vanderslott and Claas Kirchhelle introduce their typhoid history research and 'Alice in Typhoidland' public engagement project. This work delves into the history of typhoid in Oxford and highlights why typhoid is still a major global health problem needing both water, sanitation, and hygiene (WASH) interventions alongside vaccines.

Did you know

"Did you know...?"

Public Engagement

From the Town Hall, through pubs, up to shopping centres – throughout October, teams from Paediatrics have been showcasing their work all over Oxford as part of the Ideas Festival.

Halting the spread of salmonella

Halting the spread of salmonella

Research

There are between 11 and 27 million estimated cases of enteric fever worldwide every year, and 75,000–220,000 deaths. Could vaccination stop the spread of these diesases in the environment?

Vaccinations and the fight against poverty

Vaccinations and the fight against poverty

Public Engagement

What does it mean to be poor in the UK and around the world? Could we eliminate this kind of inequality or is it an unavoidable part of society? This needs a lot more thought...

Pregnant women invited to take part in pioneering diabetes prevention research

Pregnant women invited to take part in pioneering diabetes prevention research

Research

Dr Matthew Snape leads a study investigating if giving small amounts of oral insulin to babies can prevent type 1 diabetes, thus allowing mothers to protect their children from injecting insulin.

Nhs features the meningitis b vaccine in its 70 years 70 discoveries campaign

NHS features the Meningitis B vaccine in its "70 years, 70 discoveries" campaign

Public Engagement Research

The National Health Service named Oxford Vaccine Group’s Meningitis B vaccination programme one of the 70 most transformative discoveries over the past 70 years.

International clinical trials day at the childrens hospital

International Clinical Trials Day at the Children's Hospital

Why do we celebrate the International Clinical Trials Day?

How do vaccines work

How do vaccines work?

To understand how vaccines work, it helps to look first at how the immune system works, because vaccines harness the natural activity of your immune system. This short animation explains how vaccines enable the body to make the right sort of antibodies to fight a particular disease.

Support for a new typhoid vaccine

Support for a new typhoid vaccine

Typhoid has been virtually eliminated in industrialised nations, but the disease still kills more than 140,000 people annually in developing countries. With the alarming spread of drug-resistant typhoid across Africa and Asia, this number could continue to rise.

Launching a typhoid vaccine study in nepal

Launching a typhoid vaccine study in Nepal

Research

On November 20, 2017, the Typhoid Vaccine Acceleration Consortium (TyVAC) vaccinated the first of 20,000 children against typhoid, successfully launching a study to assess the impact of typhoid conjugate vaccines (TCVs) in preventing typhoid among children in Nepal.

A third of health practitioners do not get vaccinated against flu

A third of health practitioners do not get vaccinated against flu

Flu vaccination uptake amongst healthcare workers in England is below the NHS target of 75%. Reasons may include mixed views on the vaccine’s effectiveness, side effects and belief they are unlikely to catch or transmit flu. Andrew J. Pollard, Professor of Paediatric Infection and Immunity, Director of Graduate Studies, Department of Paediatrics, provided an expert commentary on a recent study investigating this phenomenon.

Oxford vaccine group leads meningitis vaccine trial for teenagers

Oxford Vaccine Group leads meningitis vaccine trial for teenagers

Public Engagement Research

Researchers are working with schools around the county to find 24,000 volunteers aged 16 to 18 years to take part in the Be on the TEAM (Teenagers Against Meningitis) trial, led by the Oxford Vaccine Group at the Oxford University's Paediatrics Department with funding and support from the National Institute for Health Research (NIHR).

Be on the team teenagers against meningitis

Be on the TEAM: TEenagers Against Meningitis

Public Engagement Research

The Oxford Vaccine Group are inviting students in school year 12 to take part in a research project to understand whether immunising teenagers with vaccines against ‘Meningitis B’ could protect them and the rest of the community against these potentially deadly bacteria. This is a national study involving 24 000 year 12 students across the United Kingdom. Teenagers at participating schools are being asked to take part by local research teams involved.

Medical sciences heads to the big bang fair

Medical Sciences heads to the Big Bang Fair

Public Engagement

Researchers from NDORMS, the Department of Oncology and Wellcome Centre for Human Genetics attend the Big Bang Fair 2018 to inspire the next generation of scientists.

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