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We present a case of a 17-year-old boy with X-linked agammaglobulinemia who had mild disease when initially infected with SARS-CoV-2 but after recovering from acute infection developed fevers and a raised erythrocyte sedimentation rate that persisted for several weeks without any ongoing respiratory symptoms. Multiple nasopharyngeal swabs were found to be negative for SARS-CoV-2 during the febrile period, but typical changes of COVID-19 on high resolution CT chest scan led to the detection of SARS-CoV-2 on RT-PCR in a sample from a bronchoalveolar lavage. His fevers completely resolved after a 5-day course of remdesivir.

Original publication




Journal article


Pediatr Infect Dis J

Publication Date





e472 - e474


Adenosine Monophosphate, Adolescent, Agammaglobulinemia, Alanine, Antibodies, Viral, Antiviral Agents, Biomarkers, Bronchoalveolar Lavage Fluid, COVID-19, Fever, Genetic Diseases, X-Linked, Humans, Inflammation, Male, Pneumonia, Viral, SARS-CoV-2, COVID-19 Drug Treatment