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© Springer International Publishing Switzerland 2016. The spectrum of meningococcal infection ranges from asymptomatic carriage in the nasopharynx to fulminant septic shock, which can result in death within a few hours of symptom onset. Classical meningococcal septicemia is one of the most recognizable clinical syndromes, with fever and widespread purpura, often in the presence of shock.

Original publication





Book title

Handbook of Meningococcal Disease Management

Publication Date



57 - 73