Rhinoviruses (RV) are ubiquitous respiratory tract pathogens. They affect both the upper and lower respiratory tract and cause colds but have also been associated with wheezing, asthma exacerbations and pneumonia. New blood transcription profiling techniques of the host immune response are becoming available to characterise the pathogenesis of RV in humans. This review will outline the clinical impact of RVs in children.

Original publication

DOI

10.1016/s0163-4453(17)30190-1

Type

Journal article

Journal

The Journal of infection

Publication Date

06/2017

Volume

74 Suppl 1

Pages

S41 - S46

Addresses

Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and the NIHR Oxford Biomedical Research Centre, Level 2, Children's Hospital, Oxford OX3 9DU, UK. Electronic address: simon.drysdale@paediatrics.ox.ac.uk.

Keywords

Humans, Rhinovirus, Pneumonia, Viral, Common Cold, Asthma, Respiratory Sounds