Websites
Xinxue Liu
Associate professor of medical statistics and epidemiology
I completed a Preventive Medicine Degree at Peking University. After that, I was trained in Epidemiology and Biostatistics at Peking University and University of Cambridge and obtained my PhD and MPhil degrees.
I joined the Oxford Vaccine Group Department of Paediatrics in 2017 after receiving more than 4 years of training as a Research Fellow (Clinical Trial Statistician) at the Imperial Clinical Trial Unit.
My experiences in trials cover a broad range of therapeutic areas, including cancer, surgery, nutrition and vaccination and ranging from early phase to late phase. My research interest is mainly in developing efficient trial designs and practical implementation of such designs in clinical trials, for example, model based adaptive designs in early phase dose-finding trials evaluating safety and efficacy. I am also interested in applying biomarkers in late phase trial design and benefit and risk assessment.
Recent publications
8-year vaccine protection following a single dose of Vi-tetanus toxoid conjugate vaccine in children in Nepal (TyVOID): a prospective cohort follow-up study of the TyVAC Nepal randomised controlled trial.
Journal article
Pant D. et al, (2027), The Lancet. Global health
Impact of dosing interval on immunogenicity following a heterologous typhoid conjugate vaccine booster in Nepalese children: an observational study.
Journal article
Zhang Y. et al, (2026), J Infect
COVID-19 vaccine effectiveness and SARS-CoV-2 variants in Nepal: Test-negative case-control study and genetic sequencing (COVVAR Nepal)
Journal article
Pokhrel B. et al, (2026), Vaccine X, 31
Typhoid Seroepidemiology for TCV Decision‑Making Meeting Report of the 18 July 2025 Expert Consultation
Preprint
Laurens M. et al, (2026)

