Terrence Chan
MSc BMBS MRCP (UK)
DPhil Student & Clinical Research Fellow
Terrence is a DPhil student and Clinical Research Fellow at the Oxford Vaccine Group, currently working on a wide range of adult vaccine clinical trials and Human Challenge studies. He completed his medical degree and Master's by Research at the University of Exeter, followed by medical training in London and obtained his Membership of the Royal College of Physicians.
Terrence is currently working to define tissue-based mechanisms of vaccine immunogenicity and how it is affected by ageing as part of the Lymph nodE single-cell Genomics AnCestrY and ageing (LEGACY) Network, with the use of single cell omics, spatial transcriptomics and Bayesian modelling to contribute to a better understanding of tissue‐based immunology and to aid vaccine design
Terrence previously served as the lead fellow in Phase 1 and Phase 3 mRNA vaccine trials targeting COVID-19 and pandemic Influenza at the St George’s Vaccine Institute. He has also been involved in NeuroHIV clinical research, primarily focusing on characterizing neurological syndromes in HIV, such as CSF HIV RNA escape and CD8 encephalitis.
Recent publications
Early lymph node T follicular helper cell signalling hub drives influenza vaccine response in an ancestrally diverse cohort.
Journal article
Siu JHY. et al, (2025), EBioMedicine, 122
Relapse of neurosymptomatic cerebrospinal fluid HIV RNA escape.
Journal article
Chan TY-H. et al, (2023), HIV Med, 24, 1158 - 1163
Electrical Cardioversion for Persistent Atrial Fibrillation in the Era of Catheter Ablation: A Real-world Observational Study
Journal article
Umeojiako WI. et al, (2022), European Journal of Arrhythmia & Electrophysiology, 8, 25 - 25
Evaluation of the Implementation of the 4C Mortality Score in United Kingdom hospitals during the second pandemic wave
Preprint
Blunsum AE. et al, (2021)
The symptomatology of cerebrospinal fluid HIV RNA escape: a large case-series.
Journal article
Chan TY-H. et al, (2021), AIDS, 35, 2341 - 2346

