Yiyuan Zhang

PhD, MSc, BSc

Medical Statistician

I joined the Oxford Vaccine Group Department of Paediatrics in 2020 after I obtained my PhD and MSc degrees in Statistics at the University of Warwick.

Currently, I work on vaccine studies, including typhoid, paratyphoid, Nipah virus, and Crimean-Congo haemorrhagic fever vaccine trials.

My PhD project is modelling telemonitored physical activity based on hidden Markov modelling with application to analysing circadian rhythm in shift workers.

Recent publications

The effect of pneumococcal conjugate vaccine and pneumococcal polysaccharide vaccine on nasopharyngeal colonisation following human infection challenge with serotype 3 and serotype 6B (PREVENTING PNEUMO 2): a double-masked, randomised, controlled, phase 4 trial.

Liatsikos K. et al, (2026), Lancet Microbe

Impact of Dosing Interval on Immunogenicity Following a Heterologous Typhoid Conjugate Vaccine Booster in Nepalese Children: An Observational Study

Zhang Y. et al, (2026)

Persistence of Immune Responses 5 Years After Vaccination With a Single Dose of Typhoid Conjugate Vaccine (TCV) in Nepalese Children

Pant D. et al, (2026)

Eight-Year Vaccine Protection Following a Single Dose of VI-Tetanus Toxoid Conjugate Vaccine in Nepali Children: Extended Follow-Up of the TyVAC Nepal Randomised Controlled Trial

Pant D. et al, (2026)

The validity of test-negative design for assessment of typhoid conjugate vaccine protection: comparison of estimates by different study designs using data from a cluster-randomised controlled trial.

Feng S. et al, (2025), Lancet Glob Health, 13, e1122 - e1131

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