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Oxford COVID-19 vaccine programme opens for clinical trial recruitment


University of Oxford researchers working in an unprecedented vaccine development effort to prevent COVID-19 have started screening healthy volunteers (aged 18-55) today for their upcoming ChAdOx1 nCoV-19 vaccine trial in the Thames Valley Region. The vaccine based on an adenovirus vaccine vector and the SARS-CoV-2 spike protein is already in production but won’t be ready for some weeks still.

COVID-19 vaccine development

A vaccine candidate for COVID-19 has been identified by researchers from the Oxford Vaccine Group and Oxford's Jenner Institute.

Alice in Typhoidland: Join Lewis Carroll’s Alice on a journey through the story of typhoid, from Victorian sewer systems to cutting-edge scientific research

Public Engagement

A new exhibition tells the story of Oxford’s role in the fight against typhoid, from pioneering efforts to eliminate typhoid in the era of Lewis Carroll’s Alice in Wonderland to game-changing present-day vaccine trials.

Typhoid vaccine over 81% effective in tackling disease in Nepal


A large field study of typhoid conjugate vaccine (TCV) in Nepal has shown a single dose to be safe and effective in reducing typhoid in children aged 9 months to <16 years in an endemic setting.

Ebola vaccine approved as second jab trialled

It’s very exciting to see that the Ad26.ZEBOV/MVA-BN-Filo Ebola vaccine schedule is being used in a large-scale study in the Democratic Republic of Congo. This is an important step towards having multiple vaccine strategies available to fight this dreadful illness, as is the recent application for marketing authorisation of this schedule by the European Medicines Agency.

Typhoid: A ghost of the past that never really went away

For most people living in the United States and Europe, typhoid is a distant memory, a ghost of a disease from another time. But typhoid never disappeared. For many people living in low- and middle-income countries, typhoid is endemic and an all too common risk faced predominately by children.

Decades neglecting an ancient disease has triggered a health emergency around the world

OVG researcher gives both modern and historical perspectives on typhoid outbreaks in her latest article for The Conversation.

International neglect of typhoid outside rich countries threatens a new global health emergency

The emergence of untreatable strains of typhoid threatens a new global health emergency that requires urgent collective action, argue experts from the Oxford Martin School in the journal Clinical Infectious Diseases today.

Is mandatory vaccination the best way to tackle falling rates of childhood immunisation?

Public Engagement

Following the publication of figures showing UK childhood vaccination rates have fallen for the fifth year in a row, researchers from OVG and the Oxford Martin Programme on Collective Responsibility for Infectious Disease discuss possible responses.

Professor Pollard among the world's most distinguished paediatricians

Awards & Appointments

Congratulations to Professor Andrew Pollard, named as one of three 2019 Rosén von Rosenstein laureates.

Solving the riddle of the typhoid toxin


Salmonella Typhi bacteria can invade the intestines and blood and lead to a disease called typhoid fever – a disease that affects around 11 million people each year globally.

The global value of vaccination


We recently worked with Mediaplanet on the 2019 Health Awareness: Value of Vaccines campaign. The campaign features exclusive content from key thought leaders and industry voices about the critical importance of full immunisation throughout life.

Should vaccines be made compulsory?

Dr Samantha Vanderslott (Oxford Vaccine Group), Dr Eleanor Draeger (sexual health expert and medical writer), and Professor Beate Kampmann (London School of Hygiene and Tropical Medicine) debate compulsory vaccination. Presented by Philippa Thomas on BBC World service.

The key to better childhood vaccines might be in our DNA

Publication Research

PBS features Daniel O'Connor's research on how children's genetic profiles affect their immunity.

Paediatrics celebrates International Clinical Trials Day

Public Engagement

Sign up to take part in our clinical trials, talk to the research staff, or simply enjoy a Microbe Mugshot Match or a Game of Crohn's (Disease).

How was typhoid eliminated in the past?

Public Engagement Research

Drs Samantha Vanderslott and Claas Kirchhelle introduce their typhoid history research and 'Alice in Typhoidland' public engagement project. This work delves into the history of typhoid in Oxford and highlights why typhoid is still a major global health problem needing both water, sanitation, and hygiene (WASH) interventions alongside vaccines.

"Did you know...?"

Public Engagement

From the Town Hall, through pubs, up to shopping centres – throughout October, teams from Paediatrics have been showcasing their work all over Oxford as part of the Ideas Festival.

Halting the spread of salmonella


There are between 11 and 27 million estimated cases of enteric fever worldwide every year, and 75,000–220,000 deaths. Could vaccination stop the spread of these diesases in the environment?

Vaccinations and the fight against poverty

Public Engagement

What does it mean to be poor in the UK and around the world? Could we eliminate this kind of inequality or is it an unavoidable part of society? This needs a lot more thought...

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