Research groups
Elizabeth Clutterbuck
Researcher
Biography
I am a BRC and James Martin School funded Post Doctoral Researcher in the OVG lab, mainly working on B cell studies based around the clinical trials. Prior to working in OVG I completed and MSc in Immunology at Kings College London, followed by an 18 month post as a Guest Researcher in the Respiratory Diseases Branch at CDC in Atlanta. I completed my PhD with Andy at OVG, finishing in 2008. My main focus now is on B cell responses to vaccine antigens and I have developed assays to identify antigen specific B cells by ELISpot and Flow Cytometry. This work has been applied to studies both in the UK and in Fiji where the data are being used to help optimise pneumococcal vaccine schedules.
Recent publications
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The Impact of Infant Bacille Calmette-Guérin Vaccination on the Immunogenicity of Other Vaccines: A Randomized Exploratory Study.
Maytum A. et al, (2024), Pediatr Infect Dis J
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An adenoviral-vectored vaccine confers seroprotection against capsular group B meningococcal disease.
Dold C. et al, (2023), Sci Transl Med, 15
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Persistence of immune response in heterologous COVID vaccination schedules in the Com-COV2 study - A single-blind, randomised trial incorporating mRNA, viral-vector and protein-adjuvant vaccines.
Shaw RH. et al, (2023), J Infect, 86, 574 - 583
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Persistence of the immune response after two doses of ChAdOx1 nCov-19 (AZD1222): 1 year of follow up of two randomised controlled trials
EWER K., (2023), Clinical and Experimental Immunology
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Human leukocyte antigen alleles associate with COVID-19 vaccine immunogenicity and risk of breakthrough infection.
Mentzer AJ. et al, (2023), Nat Med, 29, 147 - 157