Websites
Xinxue Liu
Associate professor of medical statistics and epidemiology
I completed a Preventive Medicine Degree at Peking University. After that, I was trained in Epidemiology and Biostatistics at Peking University and University of Cambridge and obtained my PhD and MPhil degrees.
I joined the Oxford Vaccine Group Department of Paediatrics in 2017 after receiving more than 4 years of training as a Research Fellow (Clinical Trial Statistician) at the Imperial Clinical Trial Unit.
My experiences in trials cover a broad range of therapeutic areas, including cancer, surgery, nutrition and vaccination and ranging from early phase to late phase. My research interest is mainly in developing efficient trial designs and practical implementation of such designs in clinical trials, for example, model based adaptive designs in early phase dose-finding trials evaluating safety and efficacy. I am also interested in applying biomarkers in late phase trial design and benefit and risk assessment.
Recent publications
Predicting Salmonella Typhi incidence using prevalence metrics from sentinel studies of community-onset bloodstream infections
Preprint
Hagedoorn N. et al, (2026)
The effect of pneumococcal conjugate vaccine and pneumococcal polysaccharide vaccine on nasopharyngeal colonisation following human infection challenge with serotype 3 and serotype 6B (PREVENTING PNEUMO 2): a double-masked, randomised, controlled, phase 4 trial.
Journal article
Liatsikos K. et al, (2026), Lancet Microbe
SARS-CoV-2-Specific Immune Responses to Vaccination in Children and Adolescents with Suppressed Immune Systems: A Prospective, Observational Study.
Journal article
Brugha R. et al, (2026), J Pediatr, 289
Maternal views on RSV vaccination in the UK's second season.
Journal article
O'Hagan S. et al, (2026), Lancet Infect Dis
Phase II multicentre double-blind randomised controlled trial of a Bivalent VaccInation against Salmonella Typhi and Paratyphi A (BiVISTA) using a controlled human infection model of paratyphoid A infection: study protocol.
Journal article
Paganotti Vicentine M. et al, (2026), BMJ Open, 16

