I joined the Oxford Vaccine Group as a senior statistician in 2017 after receiving more than 4 years of training as a Research Fellow (Clinical Trial Statistician) at the Imperial Clinical Trial Unit.
My experiences in trials cover a broad range of therapeutic areas, including cancer, surgery, nutrition and vaccination and ranging from early phase to late phase. My research interest is mainly in developing efficient trial designs and practical implementation of such designs in clinical trials, for example, model based adaptive designs in early phase dose-finding trials evaluating safety and efficacy. I am also interested in applying biomarkers in late phase trial design and benefit and risk assessment.
I am actively involved in postgraduate teaching. I designed a 4-hour training course ‘Introduction to Statistics’ for MSc in Cancer Biology students and was co-leader of the ‘Introduction to Statistics R practical module’ for MSc in Epidemiology students while working at the Imperial College London. I have also been involved in tutoring in a few other courses, such as Bayesian Statistics and Advanced Topics in Biostatistics. I have supervised two MSc students for their summer projects and one NIHR Research Methods Fellow at the Imperial Clinical Trial Unit.
I completed a Preventive Medicine Degree at Peking University in 2005. After that, I was trained in Epidemiology and Biostatistics at Peking University and University of Cambridge and obtained my PhD and MPhil degrees.
Logistics of Implementing a Large-scale Typhoid Vaccine Trial in Kathmandu, Nepal.
Colin-Jones R. et al, (2019), Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 68, S138 - S145
Assessing the Impact of a Vi-polysaccharide Conjugate Vaccine in Preventing Typhoid Infection Among Bangladeshi Children: A Protocol for a Phase IIIb Trial.
Theiss-Nyland K. et al, (2019), Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 68, S74 - S82
The design and analysis of seroefficacy studies for typhoid conjugate vaccines
LIU X. et al, (2019), Clinical Infectious Diseases
Cost-effectiveness analysis of a randomized clinical trial of early versus deferred endovenous ablation of superficial venous reflux in patients with venous ulceration.
Epstein DM. et al, (2019), Br J Surg
Impact of breast milk intake on body composition at term in very preterm babies: secondary analysis of the Nutritional Evaluation and Optimisation in Neonates randomised controlled trial
Li Y. et al, (2018), Archives of disease in childhood. Fetal and neonatal edition