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Read about the COVID-19 Oxford Vaccine Trial.

Trial participant having a blood sample taken.

Oxford scientists: how we developed our COVID-19 vaccine in record time

The pandemic is only a year old, but we already have multiple vaccines available to fight COVID-19 – including the vaccine developed by the team at the University of Oxford. Tonia Thomas and Rachel Colin-Jones describe the process that led to this scientific success.

Professor Katie Ewer and Dr Maheshi Ramasamy

Oxford vaccine researchers talk research and home-schooling on ITV's This Morning

Professor Katie Ewer (The Jenner Institute) and Dr Maheshi Ramasamy (Oxford Vaccine Group) appeared on ITV's This Morning on Wednesday 6 January to talk about their work developing the ChAdOx1 nCoV-19 coronavirus vaccine, all while juggling the demands of young families and home-schooling.

Oxford's coronavirus vaccine received regulatory approval from the MHRA

Oxford University welcomes UK regulatory emergency use authorisation of coronavirus vaccine

The University of Oxford welcomes the news that the UK Government has today accepted the recommendation from the Medicines and Healthcare products Regulatory Agency (MHRA) to authorise the emergency use of the ChAdOx1 nCoV-19 coronavirus vaccine in the UK.

Researcher working on immunology in the lab

Oxford vaccine stimulates broad antibody and T cell functions

Researchers from the University of Oxford have published further data from the Phase I/II clinical trials of the ChAdOx1 nCoV-19 coronavirus vaccine, evidencing the decision to move to a two-dose regimen in ongoing phase III trials, and how ChAdOx1 nCov-19 induces broad antibody and T cell functions.

Scientists analyzing covid 19 sample with microscope and holding covid 19 blood sample tube

Oxford vaccine team shortlisted for parliamentary awards

The University of Oxford team who have developed a COVID-19 vaccine in record time have been shortlisted for the Excellence in Healthcare Award at the NHS Parliamentary Awards.

SIMON Says…

Researchers at Oxford Vaccine Group have developed machine learning software to predict the efficacy of flu vaccines, offering huge potential for other vaccine research.

Take part in a clinical trial – see a list of all the trials we are currently recruiting to.

Child being vaccinated

Non-COVID research statement

The Oxford Vaccine Group will be continuing with some of our non-COVID research, particularly our paediatric studies, during the COVID-19 pandemic. This is because as part of these studies we give babies their routine primary immunisations on behalf of their GPs. This reduces the administrative burden on the NHS, allowing them to free up capacity and prioritise their workload to be focused on doing what is necessary to manage the response to the COVID-19 pandemic. The participants also benefit from having the vaccines in the safety of their homes or a convenient location.

Vaccine Knowledge

The Vaccine Knowledge Project aims to be a source of independent information about vaccines and infectious diseases.

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Research

Vaccines are a key component of global health policy and are essential in the defence of the health of young children. Our research focuses on the development and evaluation of new and improved vaccines.

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Events and Training

We are committed to providing high quality education and training, together with research updates for medical professionals and all those involved in the area of vaccines and paediatric and adult infectious diseases.

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There are a number of ways in which you can get involved in our research, inform our research and find out more about our work. To find out more about any of these options, follow the link below.

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Latest publications

Immunogenicity of the UK group B meningococcal vaccine (4CMenB) schedule against groups B and C meningococcal strains (Sched3): outcomes of a multicentre, open-label, randomised controlled trial.
Journal article

Davis K. et al, (2021), Lancet Infect Dis
Publisher Correction: A guide to vaccinology: from basic principles to new developments
Journal article

Pollard AJ. and Bijker EM., (2021), Nature Reviews Immunology
SIMON: Open-Source Knowledge Discovery Platform
Journal article

Tomic A. et al, (2021), Patterns, 2, 100178 - 100178
Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial
Journal article

Ramasamy MN. et al, (2021), Lancet, 396, 1979 - 1993
A guide to vaccinology: from basic principles to new developments.
Journal article

Pollard AJ. and Bijker EM., (2020), Nat Rev Immunol

How does herd immunity work?

‘Herd immunity’ or 'herd protection' gives protection to vulnerable people such as newborn babies, elderly people and those who are too sick to be vaccinated.

How to make a vaccine in record time

Vaccines usually take decades to develop – so how is Oxford University's ChAdOx1 nCoV-1 vaccine trial moving so quickly? It comes down to careful planning, extraordinary logistics and a whole lot of help from partners around the world.