Typhoid: A ghost of the past that never really went away
For most people living in the United States and Europe, typhoid is a distant memory, a ghost of a disease from another time. But typhoid never disappeared. For many people living in low- and middle-income countries, typhoid is endemic and an all too common risk faced predominately by children.
Read moreDecades neglecting an ancient disease has triggered a health emergency around the world
OVG researcher gives both modern and historical perspectives on typhoid outbreaks in her latest article for The Conversation.
Read moreIs mandatory vaccination the best way to tackle falling rates of childhood immunisation?
Following the publication of figures showing UK childhood vaccination rates have fallen for the fifth year in a row, researchers from OVG and the Oxford Martin Programme on Collective Responsibility for Infectious Disease discuss possible responses.
Read moreTyphoid vaccine over 81% effective in tackling disease in Nepal
A large field study of typhoid conjugate vaccine (TCV) in Nepal has shown a single dose to be safe and effective in reducing typhoid in children aged 9 months to <16 years in an endemic setting.
Read moreInternational neglect of typhoid outside rich countries threatens a new global health emergency
The emergence of untreatable strains of typhoid threatens a new global health emergency that requires urgent collective action, argue experts from the Oxford Martin School in the journal Clinical Infectious Diseases today.
Read moreEbola vaccine approved as second jab trialled
It’s very exciting to see that the Ad26.ZEBOV/MVA-BN-Filo Ebola vaccine schedule is being used in a large-scale study in the Democratic Republic of Congo. This is an important step towards having multiple vaccine strategies available to fight this dreadful illness, as is the recent application for marketing authorisation of this schedule by the European Medicines Agency.
Read moreProfessor Pollard among the world's most distinguished paediatricians
Congratulations to Professor Andrew Pollard, named as one of three 2019 Rosén von Rosenstein laureates.
Read moreTake part in a clinical trial – see a list of all the trials we are currently recruiting to.
stop TYPHOID An educational resource about typhoid – visit http://www.stoptyphoid.org
If you're not immune to measles you can catch it just by going into a room up to 2 hours after an infected person has left it!
Research
Vaccines are a key component of global health policy and are essential in the defence of the health of young children. Our research focuses on the development and evaluation of new and improved vaccines.
Events and Training
We are committed to providing high quality education and training, together with research updates for medical professionals and all those involved in the area of vaccines and paediatric and adult infectious diseases.
Get involved
There are a number of ways in which you can get involved in our research, inform our research and find out more about our work. To find out more about any of these options, follow the link below.
Vaccine Knowledge
The Vaccine Knowledge Project aims to be a source of independent information about vaccines and infectious diseases.
See moreValue of Vaccines campaign
We recently worked with Mediaplanet on the 2019 Health Awareness: Value of Vaccines campaign. The campaign features exclusive content from key thought leaders and industry voices about the critical importance of full immunisation throughout life.
Take a look!What's new
Typhoid vaccine over 81% effective in tackling disease in Nepal
5 December 2019
A large field study of typhoid conjugate vaccine (TCV) in Nepal has shown a single dose to be safe and effective in reducing typhoid in children aged 9 months to <16 years in an endemic setting.
Ebola vaccine approved as second jab trialled
14 November 2019
It’s very exciting to see that the Ad26.ZEBOV/MVA-BN-Filo Ebola vaccine schedule is being used in a large-scale study in the Democratic Republic of Congo. This is an important step towards having multiple vaccine strategies available to fight this dreadful illness, as is the recent application for marketing authorisation of this schedule by the European Medicines Agency.
Typhoid: A ghost of the past that never really went away
7 November 2019
For most people living in the United States and Europe, typhoid is a distant memory, a ghost of a disease from another time. But typhoid never disappeared. For many people living in low- and middle-income countries, typhoid is endemic and an all too common risk faced predominately by children.
Latest publications
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Phase 3 Efficacy Analysis of a Typhoid Conjugate Vaccine Trial in Nepal.
Journal article
Shakya M. et al, (2019), N Engl J Med, 381, 2209 - 2218
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The Future of Vaccines for Tuberculosis.
Journal article
Stockdale L. and Fletcher H., (2019), Clin Chest Med, 40, 849 - 856
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Neonatal Antifungal Consumption Is Dominated by Prophylactic Use; Outcomes From The Pediatric Antifungal Stewardship
Journal article
Ferreras-Antolín L. et al, (2019), The Pediatric Infectious Disease Journal, 38, 1219 - 1223
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Plasma lipid profiles discriminate bacterial from viral infection in febrile children.
Journal article
Wang X. et al, (2019), Sci Rep, 9
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Under-detection of blood culture-positive enteric fever cases: the impact of missing data and methods for adjusting incidence estimates
Journal article
VOYSEY M. et al, (2019), PLoS Neglected Tropical Diseases
Upcoming events
Introduction to Immunisations
Tuesday, 25 February 2020 to Wednesday, 26 February 2020, 9am - 4pm
Free 2-day Training Event for general practice nurses and health professionals new to immunisation practice who administer / promote / advise about vaccines in the Thames Valley. Funding for this event is from NHS England through Health Education England.
OVG Immunisation Seminar
Thursday, 19 March 2020 @ Kassam Stadium Conference Centre, Grenoble Road, Oxford, OX4 4XP
The annual Immunisation Seminar will be held at the Kassam Stadium Conference Centre, Oxford. It provides the ideal opportunity for practitioners to update their current immunisation knowledge and to hear the latest news on the topic of vaccination.
Hot Topics In Infection And Immunity In Children - IIC 2020
Monday, 29 June 2020 to Wednesday, 01 July 2020 @ St Catherine's College, Manor Road, Oxford, OX1 3UJ
IIC - The ESPID-Oxford Course is a residential training course covering topics in paediatric infection for paediatric infectious diseases trainees and trainers, and for all those who manage children with infections. This will be the 18th edition of the course.
