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OVG Researcher awarded prestigious NIHR Professorship

Daniela Ferreira, Professor of Respiratory Infection and Vaccinology at the University of Oxford’s Department of Paediatrics and the Department of Clinical Sciences at the Liverpool School of Tropical Medicine has been awarded one of six prestigious Research Professorships by the National Institute of Health and Care Research (NIHR).

CEPI funding announced for development of vaccine prototype

The University of Oxford and the Coalition for Epidemic Preparedness Innovations (CEPI) today announced the launch of a new project to initiate early development of prototype vaccines against the Junín virus, selected as an exemplar of the Arenavirus family which is responsible for multiple deadly haemorrhagic fevers with epidemic and pandemic potential.

Oxford launches new vaccine trial to enhance design of flu & COVID-19 vaccines

A pioneering study into human immunity is being launched today by Oxford Vaccine Group at the University of Oxford. The study, called LEGACY03, is being funded by the Medical Research Council part of UK Research and Innovation. By investigating how lymph nodes work, and how they make responses to vaccines in younger and older people, it has the potential to improve vaccine design for different age groups significantly.

Future of Chair in Global Health secured with £5 million gift

The University of Oxford’s commitment to tackling major global health challenges has been strengthened following the endowment of a chair in global health and clinical development. The new permanent post was made possible by a £5 million donation from Brazilian healthcare organisation SAIL for Health.

First vaccine trial in older people launched for Middle East Respiratory Syndrome (MERS)

Researchers at the University of Oxford's Pandemic Sciences Institute have launched a new clinical trial to find a vaccine to protect people against Middle East Respiratory Syndrome (MERS).

First in-human trials commence for CCHF vaccine

A University of Oxford study has administered a new vaccine against tick-borne virus Crimean-Congo haemorrhagic fever (CCHF) to human volunteers for the first time. The clinical trial of the ChAdOx2 CCHF vaccine aims to confirm its safety and understand how individuals develop immunity following vaccination.

University of Oxford partners with CEPI to counter the threat of future pandemics

The University of Oxford and the Coalition for Epidemic Preparedness Innovations (CEPI) have entered into a strategic partnership to accelerate the development of safe, effective and globally accessible vaccines to counter the threat of future pandemics.

Director of Global Operations at OVG recognised in the King’s Birthday Honours 2023

Dr Parvinder Aley, Director of Global Operations at the Oxford Vaccine Group, has been recognised and celebrated in the 2023 King’s Birthday Honours list. Dr Aley has been appointed an Officer of the Order of the British Empire (OBE) for services to vaccination during the COVID-19 pandemic.

Professor Sir Andrew Pollard reveals unique insights into the world of science in a new podcast

Oxford Vaccine Group and Pandemic Sciences Institute’s Professor Pollard speaks to the people who shaped the COVID-19 pandemic in his new podcast, The Oxford Colloquy.

Britain’s Covid research led the world – why have our clinical trials fallen off a cliff?

Pressures on the NHS, a lack of doctors and post-Brexit delays are hampering our ability to develop cutting-edge drugs.

Take part in a clinical trial – see a list of all the trials we are currently recruiting to.

Child being vaccinated

Non-COVID research statement

The Oxford Vaccine Group will be continuing with some of our non-COVID research, particularly our paediatric studies, during the COVID-19 pandemic. This is because as part of these studies we give babies their routine primary immunisations on behalf of their GPs. This reduces the administrative burden on the NHS, allowing them to free up capacity and prioritise their workload to be focused on doing what is necessary to manage the response to the COVID-19 pandemic. The participants also benefit from having the vaccines in the safety of their homes or a convenient location.

Vaccine Knowledge

The Vaccine Knowledge Project aims to be a source of independent information about vaccines and infectious diseases.

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Research

Vaccines are a key component of global health policy and are essential in the defence of the health of young children. Our research focuses on the development and evaluation of new and improved vaccines.

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We are committed to providing high quality education and training, together with research updates for medical professionals and all those involved in the area of vaccines and paediatric and adult infectious diseases.

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There are a number of ways in which you can get involved in our research, inform our research and find out more about our work. To find out more about any of these options, follow the link below.

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Latest publications

Identification of circulating monocytes as producers of tuberculosis disease biomarker C1q
Journal article

Niewold P. et al, (2023), Scientific Reports, 13
The collective voice of early phase COVID-19 vaccine trial participants: Insights for improving confidence in novel vaccines.
Journal article

Thomas TM. et al, (2023), Human vaccines & immunotherapeutics, 19, 2203023 - 2203023
Association Among Household Water, Sanitation, and Hygiene (WASH) Status and Typhoid Risk in Urban Slums: Prospective Cohort Study in Bangladesh.
Journal article

Tadesse BT. et al, (2023), JMIR Public Health Surveill, 9
Salmonella Vaccine Study in Oxford (SALVO) trial: protocol for an observer-participant blind randomised placebo-controlled trial of the iNTS-GMMA vaccine within a European cohort.
Journal article

Hanumunthadu B. et al, (2023), BMJ Open, 13
Intravenous immunoglobulin treatment in childhood encephalitis (IgNiTE): a randomised controlled trial.
Journal article

Hill M. et al, (2023), BMJ Open, 13

Upcoming events

19th Annual OVG Immunisation Seminar

Thursday, 14 March 2024, 9am to 4pm @ The Kassam Conference & Events Centre, Grenoble Rd, Littlemore, Oxford OX4 4XP

A one-day seminar for HCPs providing key updates and the latest news on the topic of immunisations.

IIC 2024 - Hot Topics In Infection And Immunity In Children – The ESPID Oxford Course

Monday, 24 June 2024 to Wednesday, 26 June 2024, 10am - 2pm @ St Catherine's College Manor Road Oxford OX1 3UJ

IIC – The ESPID-Oxford Course is a residential training course covering topics in paediatric infection for paediatric infectious diseases trainees and trainers, and for all those who manage children with infections. 2024 will be the 21st edition of the course.

National Immunisation Schedule Evaluation Consortium

OVG is part of the National Immunisation Schedule Evaluation Consortium; a collaboration between a network of Academic Clinical Research groups and the UK Health Security Agency, with a brief of conducting clinical research relevant to UK immunisation policy

More about NISEC

We’ve made a vaccine, now you can make the difference

We’ve heard about how effective vaccines are, but what do we need for them to have the biggest impact on the coronavirus pandemic?

How to make a vaccine in record time

Vaccines usually take decades to develop – so how is Oxford University's ChAdOx1 nCoV-1 vaccine trial moving so quickly? It comes down to careful planning, extraordinary logistics and a whole lot of help from partners around the world.

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